Raymond P. Welch, Ph.D.

Scientist, Software Developer, Artist

Find Out More

Scientist, Software Developer, Artist

I enjoy doing science and helping others do science! I love electron microscopy, particularly of the TEM variety. I have experience preparing and imaging viral, bacterial, and inorganic samples, both at room temperature and at cryogenic temperatures.

I also enjoy writing code! I have experience with console applications using continuous integration, unit tests, version control, and collaboration. I also have experience with full-stack web application development and maintenence.

I love to work with my hands! I have expereince with blacksmithing, sculpting, and drawing, and I like to create.

Here are some of my projects

Projects

What I Have Been Working On

Dungeon Patron

Invest in dungeon-delving adventuring parties!

Sculpting

Polymer clay figurines!

Drawing

Pencil and Digital!

Games

Western-themed Action Rogueish!

Curriculum Vitae

Comprehensive Experience

Education

Doctor of Philosophy in Chemistry (May 2019)

University of Texas at Dallas
Richardson, TX, USA
Dissertation: “Controlling Thermal Effects on Chemical Systems”
Advisor: Professor Jeremiah. J. Gassensmith

Bachelor of Science in Chemistry (Dec 2013)

University of North Texas
Denton, TX, USA
Minor in Mathematics

Bachelor of Science in Electrical Engineering (Dec 2013)

University of North Texas
Denton, TX, USA
Minor in Mathematics

Proficiencies

Chemical Methods

ELISA, Protein assays (Lowry, Bradford), Small molecule synthesis, Plant virus isolations, Bacterial protein expression and purification, MOF synthesis

Instrumentation Methods

TEM (Biological, CryoTEM, tomography, negative stain), Plunge freezing, SEM, UV-Vis spectroscopy, Circular dichroism spectroscopy, NMR spectroscopy, HPLC, ESI-MS, FT-IR spectroscopy, Fluorescence spectroscopy, XPS, DLS, PXRD, Ultramicrotomy

Management

Team management, Lab management (Inventory, Waste, Instrument upkeep and maintenance, Scheduling), System and protocol organization

Software and Programming

C#, T-SQL, ASP.NET, MVC, Microsoft Office (Word, Excel, PowerPoint, OneNote), Adobe CS6 (Illustrator, Premiere, Photoshop), Chemdraw, Origin, TopSpin, C++, VHDL, LabView, MATLAB

Other

UHV chamber construction and maintenance, Blacksmithing

Work

Software Developer

dungeonpatron.com
May 2019 - Present
Hurst, TX

Personal Shopper

Online Grocery Pickup
Walmart
Dec 2019 - Present
Weatherford, TX – Hurst, TX

Graduate Research Assistant

Gassensmith Lab
University of Texas at Dallas
Jan 2015 – May 2019
Richardson, TX
Research Advisor: Dr. Jeremiah. J. Gassensmith

Graduate Teaching Assistant

Dept. of Chemistry and Biochemistry
University of Texas at Dallas
Aug 2014 – May 2019
Richardson, TX
TA Coordinator: Dr. Gregg Dieckmann

Lab Attendant and Consultant

Matthews Hall General Access Computer Lab
University of North Texas
Jan 2008 – May 2014
Denton, TX

Undergraduate Research Assistant

Kelber Lab
University of North Texas
May 2012 – December 2013
Denton, TX
Research Advisor: Dr. Jeffry A. Kelber

Research

Gassensmith Lab

University of Texas at Dallas
Department of Chemistry and Biochemistry
Research Advisor: Dr. Jeremiah. J. Gassensmith
Aug 2014 – May 2019
Synthesis of small molecules; small molecule bioconjugation to virus-like particles (VLPs) and proteins; VLP isolation and purification from plant material; biomaterials preparation and analysis; metal-organic framework synthesis on biomaterials, biomaterials and protein antigen surface analysis; extensive electron microscopy (TEM and SEM) characterization and analysis of VLP-based materials; Lab Safety Officer and Safety Liaison; Inventory and Waste Manager, Tobacco Team Manager

Chabal Lab

University of Texas at Dallas
Department of Materials Science
Research Advisor: Dr. Yves J. Chabal
Jun 2014 – Aug 2014
Silicon surface cleaning, etching, and functionalization; quantum dot synthesis

Kelber Lab

University of North Texas
Department of Chemistry
Research Advisor: Dr. Jeffry A. Kelber
May 2012 – December 2013
Deposition of boron carbide thin films; plasma etching and deposition; building and maintenance of ultra-high vacuum chambers; magnetron sputtering

Teaching

Graduate Teaching Assistant

University of Texas at Dallas
CHEM 4473 Advanced Physical Measurements
January 2019 – May 2019
Dr. Warren Goux, Dr. Yu Huang
CHEM 3471 Advanced Synthesis
June 2017 – May 2018
Dr. Jeremiah Gassensmith, Dr. John Ferraris, Dr. Ronald Smaldone
CHEM 1111 General Chemistry Laboratory I, Safety TA
June 2016 – May 2017
Dr. Sandhya Gavva, Dr. Yanping Qin, Dr. Amandeep Sra
CHEM 1312 General Chemistry II Lecture
January 2016 – May 2016
Dr. Jason McAfee, Dr. Stephanie Taylor
CHEM 1311 General Chemistry I Lecture
August 2015 – December 2015
Dr. Jason McAfee, Dr. John Sibert
CHEM 1112 General Chemistry II Laboratory
January 2015 – July 2015
Dr. Jason McAfee, Dr. Amandeep Sra
CHEM 1111 General Chemistry I Laboratory
August 2014 – December 2014
Dr. Jason McAfee

Publications

ORCID: 0000-0003-3114-8801
1. Welch, R. P.‡; Dharmarwardana, M.‡; Caicedo-Narvaez, C.; Luzuriaga, M. A.; Arimilli, B. S.; McCandless, G. T.; Fahimi, B.; Gassensmith, J. J., Reversibly Thermosalient NDI Crystal Switch, Manuscript in Preparation ‡Denotes co-first authorship and equal contribution
2. Luzuriaga, M. A.‡; Welch, R. P.‡; Dharmarwardana, M.; Benjamin, C. E.; Li, S.; Shahrivarkevishai, A.; Popal, S; Tuong, L. H.; Creswell, C. T.; Gassensmith, J. J., Enhanced Stability and Controlled Delivery of MOF Encapsulated Vaccines and Their Immunogenic Response In Vivo. ACS Appl. Mater. Interfaces, 2019, 11 (10), 9740-9746 ‡Denotes co-first authorship and equal contribution
3. Welch, R. P.; Lee, H.; Luzuriaga, M. A.; Brohlin, O. R.; Gassensmith, J. J., Protein-Polymer Delivery: Chemistry from the Cold Chain to the Clinic. Bioconjugate Chem. 2018, 29 (9), 2867-2883.
4. Lee, H.; Benjamin, C. E.; Nowak, C. M.; Tuong, L. H.; Welch, R. P.; Chen, Z.; Dharmarwardana, M.; Murray, K. W.; Bleris, L.; D'Arcy, S.; Gassensmith, J. J., Regulating the Uptake of Viral Nanoparticles in Macrophage and Cancer Cells via a pH Switch. Mol. Pharm. 2018, 15 (8), 2984-2990
5. Li, S.; Dharmarwardana, M.; Welch, R. P.; Benjamin, C. E.; Shamir, A. M.; Nielsen, S. O.; Gassensmith, J. J., Investigation of Controlled Growth of Metal–Organic Frameworks on Anisotropic Virus Particles. ACS Appl. Mater. Interfaces 2018, 10 (21), 18161-18169.
6. Chen, Z.; Boyd, S. D.; Calvo, J. S.; Murray, K. W.; Mejia, G. L.; Benjamin, C. E.; Welch, R. P.; Winkler, D. D.; Meloni, G.; D’Arcy, S.; Gassensmith, J. J., Fluorescent Functionalization across Quaternary Structure in a Virus-like Particle. Bioconjugate Chem. 2017, 28 (9), 2277-2283.
7. Dharmarwardana, M.; Welch, R. P.; Kwon, S.; Nguyen, V. K.; McCandless, G. T.; Omary, M. A.; Gassensmith, J. J., Thermo-mechanically responsive crystalline organic cantilever. Chem. Commun. 2017, 53 (71), 9890-9893.
8. Li, S.; Dharmarwardana, M.; Welch, R. P.; Ren, Y.; Thompson, C. M.; Smaldone, R. A.; Gassensmith, J. J., Template-Directed Synthesis of Porous and Protective Core–Shell Bionanoparticles. Angew. Chem., Int. Ed. 2016, 55 (36), 10691-10696.
9. Chen, X.; Kazi, H.; Cao, Y.; Dong, B.; Pasquale, F. L.; Colón Santana, J. A.; Cao, S.; Street, M.; Welch, R.; Binek, C.; Enders, A.; Kelber, J. A.; Dowben, P. A., Ultrathin chromia films grown with preferential texture on metallic, semimetallic and insulating substrates. Mater. Chem. Phys. 2015, 149–150 (0), 113-123.
10. Pasquale, F. L.; James, R.; Welch, R.; Echeverria, E.; Dowben, P. A.; Kelber, J. A., Novel Cross-Linked Ortho-Carborane and Ortho-Carborane:Y (Y=1,4-Diaminobenzene, Pyridine, Benzene) Polymer Films: A New Class of Carborane-Based Materials with Tunable Electronic Structure. ECS Trans. 2013, 53 (1), 303-310.

Presentations

1. Welch, R P.; Luzuriaga, M. A.; Li, S.; Gassensmith, J. J., Contributed talk on “Immunoassay Investigation of Vaccine Carrier Stability Within ZIF-8 Encapsulation”, 256th ACS National Meeting, Boston, MA, USA. August 19, 2018
2. Welch, R P.; Luzuriaga, M. A.; Li, S.; Gassensmith, J. J., Contributed talk on “Immunoassay Investigation of Vaccine Carrier Stability Within ZIF-8 Encapsulation”, 51st Annual Meeting-in-Miniature (DFW ACS), Dallas, TX, USA. April 21, 2018
3. Welch, R P.; Luzuriaga, M. A.; Li, S.; Gassensmith, J. J., Contributed talk on “Immunoassay Investigation of Vaccine Carrier Stability Within ZIF-8 Encapsulation”, UT Dallas/Texas A&M Agrilife Research Extension Joint Symposium, Richardson, TX, USA. March 16, 2018
4. Welch, R P.; Li, S.; Gassensmith, J. J., Contributed talk on “Template Directed Synthesis of Porous and Protective Core-Shell Bionanoparticles”, Texas Soft Matter Meeting, Richardson, TX, USA. August 12, 2016
5. Welch, R P.; Li, S.; Gassensmith, J. J., Poster presentation on “Tobacco Mosaic Virus Stabilized By Coordination Polymers”, 251st ACS National Meeting, San Diego, CA, USA. March 13, 2016
6. Welch, R P.; Li, S.; Dharmarwardana, M.; Gassensmith, J. J., Contributed talk on “Novel Synthesis of 3D Ordered Macroporus Structures”, Texas Soft Matter Meeting, August 21, 2015

Professional Memberships

American Chemical Society: 2015 – 2020

Awards

Happy To Help Associate of the Month, Feb 2020, Walmart #963
Nominated for the 2019 President’s Teaching Excellence Award for Teaching Assistants at the University of Texas at Dallas
Contact me at:
welch (dot) raymond (at) gmail (dot) com